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Compared with the H 2 O 2 group, short-term exogenous IGF-1 treatment for 1 h did not alter the protein levels of p53 and progerin, as well as the activity of SA--gal, though p21 protein expression was downregulated

In vitiligo patients, melanocytes are particularly sensitive to oxidative damage, which disrupts TYR function, inhibits eumelanin synthesis, and ultimately impairs pigmentation 46

Metformin mitigates cartilage degradation by activating AMPK/SIRT1-Mediated autophagy in a mouse osteoarthritis model

Do not use if you are allergic or sensitive to any of the ingredients in these supplements

Since 1mL = 100 units on a standard syringe, each 10 units (0.1mL) contains 250mcg

Innovation Project of Gansu Provincial Department of Education (2024A-094)