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doi: 10.1016/j.cmet.2011.02.018 55 ManciniNLRajeevSJaymeTSWangAKeitaVWorkentineMLet al

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Excessively elevated Ang II levels enhance plasma cytokine levels such as IL-6, interferon- (IFN-), TNF-, and IL-1 (95)

433,434 Additionally, hyperglycemia triggers activate oxidative stress and inflammation, along with mitochondrial dysfunction, drawing significant attention from several researchers

Young animals and older animals can have differing metabolic rates and physiological responses