The hepatotoxicity of PZA is dose-dependent, especially at doses above 40 mg/kg, and correlates with its hepatic metabolism, suggesting a direct toxic effect rather than a hypersensitive or immune-mediated mechanism
There were no significant differences in clinical variables across groups, except for the TCQ score, which was significantly higher among those who quit smoking, indicating a greater reduction in craving within this subgroup
This is very different from a negative ion generator, or ionizer, whose primary purpose is to reduce particles like dust and pollen floating around in air spaces
In contrast, e-cigarettes only release a handful of relatively harmless chemicals when used
Retailers needed to look for a more effective way to keep meeting their customers needs
Interventions to increase adherence to medications for tobacco dependence