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A new class of potent tyrosinase inhibitors was identified by structure-based virtual screening prediction 135

There are no published human clinical trials of Dihexa, and the closest human evidence in its drug class Athira's fosgonimeton failed its Phase 3 Alzheimer's endpoint in 2024

The enhanced cardiac outcome of conjugated SGLT2 inhibitors and GLP-1RA therapy in diabetic patients

Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine

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The content of CoQ10 significantly increased in GCH1-overexpressing cells, possibly due to the abundant production of its biosynthetic precursor 4-OH-benzoate, which is dependent on BH4-mediated conversion of phenylalanine to tyrosine