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This is in accordance with the accumulated macrophage, neutrophil and lymphocyte levels in the BALF of the smoke-exposed mice, since CCL2 is a monocyte chemoattractant and is produced by multiple cell types, including monocytes, macrophages, endothelial cells and epithelial cells [76]

Manufacturing cigarettes generates an estimated 15.7 million tonnes of greenhouse gasses, 9 million tonnes of water waste and water emissions, and 1.2 million tonnes of waste each year