Reconstitute using sterile bacteriostatic water or another laboratory-approved diluent under aseptic conditions
### Discard the Vial If: - It has been more than 30 days since reconstitution - You see cloudiness, particles, or color changes - The vial was left at room temperature for more than a few hours - You suspect contamination (e.g., the stopper was touched without cleaning) When in doubt, discard and start fresh
Academic Press, Cambridge, MA, USA (2014)
Other factors implicated in the development of melasma include: Genetics: 60% of people report affected family members Thyroid disorder can be associated with melasma Medications: Certain medicines may cause melasma
Furthermore, melatonin can not only be taken up from the circulation and is produced and metabolized in mitochondria (Tan et al., 2013)
How it Works : Acts on the ghrelin receptor similarly to GHRP-6 but with fewer side effects