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The substitution of carboxamide at the alkyl terminal (KL2, KL4 and KL5) or removal of the nitrile group from the dihydropyridine ring (KL6) moderately reduced their adjuvant activity (Extended Data Fig

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This share is attributed to the growing government support for domestic manufacturing, which is likely to boost the production levels and reduce the dependence on imports in the Asia Pacific region, thereby offering lucrative opportunities to global manufacturers

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