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2b), indicating that ICP27 and symplekin may bind to CPSF complex in a mutually exclusively manner

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They are potentially safer for long-term use because they work through natural biological mechanisms rather than forcing pathways shut

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Human umbilical vein endothelial cells (HUVECs) culture HUVECs purchased from BCRC (Hsinchu, Taiwan, ROC) were grown in M199 medium supplemented with 16% fetal bovine serum and 20% EGM-2 (Clonetics, USA)