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Statistical approach We used t -tests to compare continuous outcomes based on dichotomous variables

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Nicotine is the main addictive component of cigarettes 17,18 , which has been reported to ameliorate the abnormalities in dopaminergic, glutamatergic, and GABAergic pathways 19 and has been linked to the mechanism of symptom improvements

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Nicotine Replacement Therapy (NRT) for Tobacco Addiction Nicotine Replacement Therapy (NRT) is a medically approved method to help individuals quit smoking by providing a controlled dose of nicotine without the harmful substances found in tobacco, according to a study by Wadgave U, Nagesh L

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