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A comprehensive longevity panel is the right baseline to start from

Quality control of grey-market material is also a real practical risk, separate from the molecule itself

You can find genetic testing with various companies such as 23andme.com Its estimated that those with one mutation (heterozygous) decrease their ability to methylate by 30% and those with two mutations (homozygous) decrease their ability to methylate by 70%, making it virtually impossible to get adequate B12 from diet alone (19)

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For patients on a calorie-restricted weight loss program, adequate B12 ensures fat metabolism operates at full efficiency

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