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and Waterham, H.R

Progress in NeuroPsychopharmacology & Biological Psychiatry 2011;35(4):9538

1 G6PD initiates the first step in the pentose phosphate pathway, reducing NADP into NADPH

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This interaction is thought to underpin observations of enhanced microvascular network formation in in vivo angiogenesis assays, with BPC-157 appearing to upregulate vascular endothelial growth factor receptor 2 (VEGFR2) signaling and promote endothelial cell migration and tube formation in culture