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We identified 22 Cochrane systematic reviews on behavioural interventions, pharmacotherapies, combined behavioural and pharmacotherapy interventions, and other interventions.22 We updated our search in June 2024, and findings on benefits and harms were consistent with results from earlier searches (Appendix 2, available at www.cmaj.ca/lookup/doi/10.1503/cmaj.241584/tab-related-content)

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While uncomfortable, the side effects of nicotine withdrawal are not considered dangerous

Oral herpes (HSV-1) is not usually considered an STI because most people contract it through non-sexual contact, such as kissing or sharing utensils

Fifty years ago, almost half the adults in Great Britain smoked cigarettes, but this has become much less common

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