Probably, the best research so far is a rigorous 12 week clinical trial on 30 ASD patients aged 3 to 8 years
Intracellular cysteine availability is obtained either from cysteine, cystine or methionine/serine transport (transsulphuration pathway) through the involvement of any one of the above-mentioned amino acid transporters
It is critical to note that the safety profile for injectable or systemic use is far less established due to a lack of human research
doi: 10.1055/s-2007-979981
At the time, the authors observed that, while lymphocyte atypia decreased in the blood count, the eosinophilia progressively increased, configuring a characteristic hematological evolution of what is currently called DRESS syndrome.8 In 1949, Lowe and Smith were the first to publish what would be called dapsone hypersensitivity syndrome or sulfone syndrome, when they observed a 2% incidence of development of exfoliative dermatitis in patients receiving dapsone to treat leprosy.9 In 1951, sulfone syndrome was described as a mononucleosis-like syndrome characterized by the occurrence of exfoliative dermatitis, hepatomegaly, jaundice, splenomegaly, lymphadenopathy and a predominance of mononuclear cells in the peripheral blood, in patients treated for less than two months with the drug
Even though some agents have undergone clinical trials in some areas, many others are still under investigation
