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(132), demonstrated that gut microbiota metabolites derived from dietary polyphenols (e.g., quercetin, proanthocyanidins, and kaempferol), such as 3,4-dihydroxyphenylacetic acid (3,4-DHPAA) and 4-hydroxyphenylacetic acid (4-HPAA), can counteract the immunosuppressive effects of heme on macrophages

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10.1016/j.livsci.2022.104826 [DOI] [Google Scholar] Dao H