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Coffee enemas can cause serious complications including rectal perforation, electrolyte imbalances, caffeine toxicity, and severe infections

Together our data and other studies suggest that TrxR1 acetylation is a potential mechanism to maintain higher Trx system activity

doi.org/10.1016/j.fertnstert.2024.09.038

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Randomized, blind, controlled trial of transdermal rotigotine in early Parkinson disease

In the preclinical literature it is studied primarily as a cytoprotective and angiogenic agent, meaning research examines how it may influence the survival of cells under stress and the formation of new blood vessels in laboratory models