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60,61,62 Uric acid and purines, including adenosine and adenosine triphosphate, have been implicated in regulating central nervous system functions such as convulsive threshold, memory, cognition, sleep, activity, appetite, mood, social interaction, drive, impulsivity, and intelligence

NIH summarizes evidence linking higher TMAO with cardiovascular risk, while also noting that the implications are not fully understood

Some prescription drugs achieve much larger average weight loss in trials

Haimerl P, Bernhardt U, Schindela S, Henkel FDR, Lechner A, Zissler UM, et al

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