PubMed Central , JAMA , vol
E., Yen, K., & Cohen, P
2,97 Studies and clinical practice of treatment of pernicious anaemia with regular high-dose injections has confirmed the safety of B12 at high dosages, and therefore neither the Institute of Medicine (IOM) in the USA nor the European Food Safety Agency (EFSA) have set an upper limit
Best choice: your provider can recommend the right option based on your B12 level, the cause of your deficiency, and your symptoms
However, separate formulations are used for irrigation , such as diluting, rising, and washing
If it is an oral supplement, treat the weight loss claims with healthy scepticism and look for independent, peer-reviewed evidence rather than manufacturer claims