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Another bifunctional TGF- trap fused drug, anti-CTLA4-TGF-RII, showed superior anti-tumour efficacy compared to an anti-CTLA4 antibody alone in preclinical models [336], but its efficacy in patients has not been investigated

The compound supports the work

Since the first ADC drug, Mylotarg (gemtuzumab ozogamicin), was approved by the FDA in 2000, there are currently 17 ADC drugs approved worldwide for hematologic malignancies and solid tumors

Every comparison you will read including this one is indirect , assembled from separate trials run in different populations, at different times, with different endpoints