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This study complies with relevant institutional, national, and international guidelines and legislation

Opioid peptides Dietary intake of peptides, including gluten, casein, and gliadin, may exert opioid-like effects due to incomplete degradation in the gastrointestinal system

The current branded form, Egrifta WR, was FDA-approved in March 2025 and became available in September 2025

Declarations Ethics approval and consent to participate Not applicable

Elevated blood oxalate is also associated with increased risk of cardiovascular events, in particular sudden cardiac death

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