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Patients need to learn how to do this safely, if they need to do it themselves

[5] [6] Once administered intramuscularly (usually into the deltoid or gluteal muscle), hydroxocobalamin is rapidly absorbed into the circulation

The standard prescription starts with an initial intramuscular dose

The treated area will be red for about 20 minutes immediately after the procedure, and it might feel stiff, but this normally disappears within 10 minutes