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The researchers discovered that glutamine metabolism is impaired in the obese state, leading to increased chromatin O-GlcNAcylation and activation of genes in proinflammatory pathways
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10.3390/cells10102550 197 TsukaguchiM.ShibanoM.MatsuuraA.MukaiS
The downregulation of KLF2 expression is significantly correlated with the TNM staging of ccRCC, and ccRCC patients with low expression of KLF2 have significantly shorter overall survival and metastasis-free survival periods
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