53,54 Chronic low-grade systemic inflammation elevates levels of C-reactive protein (CRP) and proinflammatory cytokines, leading to endothelial dysfunction and nerve injury
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First, it is a powerful antioxidant in its own right, neutralising free radicals and supporting collagen synthesis
Harmful hydrogen peroxide cellular levels are minimized by the enzyme glutathione peroxidase (GP) using GSH as a reductant
When Conventional Pain Treatment Fails If pain persists despite medications, injections, or physical therapy, it is often a sign that: Inflammation is being driven by systemic factors Tissue damage is not healing adequately The nervous system remains stuck in a pain-sensitive state Foundational supports like nutrition, sleep, and recovery are insufficient At this point, continuing to suppress symptoms without addressing root causes can prolong suffering rather than resolve it
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