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The safety margin between therapeutic and potentially harmful doses appears substantial

Emsley P, Cowtan K

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For background on the broader angiotensin IV / AT4 system the work was built on, see Wright and Harding 1995 (PMID 7768321) and Wright et al

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This recommendation is conservative, based on BPC-157's pharmacokinetics: absorption and distribution occur within 1-2 hours of subcutaneous injection