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Similarly, in microglia mitochondria, levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) have been shown to be regarded as a marker of DNA/ RNA oxidation due to the lack of protection of mitochondrial DNA (mtDNA) by histone proteins and its own limited repair capacity (41)

Example experimental endpoints: healing rate (time to closure), expression of repair markers (e.g., collagen I/III ratio), and functional recovery assays

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It is highly recommended to have an open discussion with your surgeon about your medical history, family history, and alcohol dependency before the surgery takes place so you can have a safe and healthy recovery

No refrigeration required