10.3390/cancers16040824
But the human evidence is thinner than for almost any substance with this level of internet popularity
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Doses of 50100 mg mean draw volumes in the mL range rather than hundredths of a mL
In the most severe variants of G6PD deficiency, e.g., those leading to chronic non-spherocytic hemolytic anemia and chronic granulomatous disease (CGD), it was observed that leukocyte G6PD activity and PPP flux were markedly reduced (25, 26), leading to diminished oxidative burst and impaired bacterial killing in phagolysosomes (27)
Clinical trials specifically using the arginate formulation would provide human pharmacokinetic data and efficacy endpoints