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The foundational obesity finding comes from Kraus and colleagues (Nature, 2014), who showed that knocking down NNMT protected mice against diet-induced obesity establishing NNMT as a metabolic target in the first place

This jives with evidence suggesting that nNOS inhibition is a mediator of anxiolytic and mood-improving effects of medications used to treat both PTSD and other anxiety/mood disorders (Zhu et al., 2023)

They are therefore a good alternative for those who might prefer a delivery method without needles or who have an allergy to injections

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This material can be in solid (limestone, chalk) or liquid (hydrated lime) forms