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[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Pedata F., Pugliese A.M., Coppi E., Dettori I., Maraula G., Cellai L., Melani A

Barrier Repair & Soothing: Combines fermented extracts, aloe vera, and allantoin to repair the skin barrier, soothe irritation, and improve overall skin health

This IL-1 associated surge in Cx43 expression was diminished by exposure of the cell line to nobiletin (Kono et al., 2022)

The risk appears low and was not dose-dependent

However, challenges persist in applying these approaches in clinical practice

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