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(Hoboken) 69 , 17511763 (2017)

In another study using HT22 cells, huperzine A (HupA) + wortmannin treatment stopped the downregulation of p-mTOR, p-Akt, and p-p70s6 kinase under oxidative glutamate toxicity, leading to the conclusion that HupA abrogates oxidative glutamate toxicity in mouse hippocampal cells via the activation of the BDNF/TrkB-dependent PI3K/Akt/mTOR signaling pathway 51

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Glutamate signaling in chondrocytes and the potential involvement of NMDA receptors in cell proliferation and inflammatory gene expression

For references and more information , see the section on cardiovascular disease in the Selenium article