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The combined effect of all three pathways creates a metabolic environment that attacks excess body fat from multiple angles simultaneously

Breakouts caused by irritation are persistent and damaging

Preventing damage by supplying electrons directly to the oxidant before it depletes electrons from the target

Predicting functional effect of human missense mutations using PolyPhen-2

In some cases, doses are adjusted after 4 to 6 weeks based on lab results (especially IGF-1 levels, a marker of GH activity) and how the patient is feeling

Funding This work was supported by an NIH (R03AG070540-0) and a VA Merit award (BX004352-01) to LA