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B12 is crucial in brain function, nerve tissue health, and red blood cell production

study timeline, Fig

Layering both can slow digestion more than either one alone

All candidates require a thorough medical evaluation, with careful screening for renal failure, hepatic insufficiency, or cardiopulmonary compromise, and close monitoring whenever glycine is administered to anyone with borderline organ function

Do not double up to compensate

Treatment typically requires intramuscular hydroxocobalamin injections (1 mg three times weekly initially, then every 23 months lifelong) when malabsorption or neurological symptoms are present