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GSH is considered the bodys master antioxidant, which is critical for the maintenance of antioxidative balance and helping to protect cells from the effects of oxidative stress.* GSH also helps promote normal detoxification.*

KARs are tetramers composed of five distinct subunits (GluK15)

New metabolic inhibitors are being developed, for instance, IACS-010750, an inhibitor of elector complex chain complex 1, a drug currently under phase I clinical trials for AML (ClinicalTrials.gov: NCT02882321) (113)

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Heerfordt IM, Philipsen PA, Lerche CM, Wulf HC

These can be seen by putting a drop of fluid on a slide and examining it using a polarizing microscope, which takes advantage of the way uric acid crystals bend light