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Redox-optimized ROS balance and the relationship between mitochondrial respiration and ROS
The expression changes in miRNAs alter the expression of their target genes, potentially decreasing the activity of oncogenes as well as increasing that of tumor suppressor and DNA repair genes [32]
At present, there is no research to prove its role in prostate cancer ferroptosis, which can be a future research direction
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Knockout of ABCC1 led to a 1.9 - 2.8-fold reduction of the GI 50 concentrations of Venetoclax and AZD-4320, while no difference in Midostaurin sensitivity was observed upon inactivation of ABCC1 (Supplementary Fig
2022;5(9):e2230439
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