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Short-chain fatty acids (SFCAs) like acetate, butyrate and propionate, derived from host microbial fermentation of non-digestible carbohydrates, transduce signals through GPCR to promote anti-inflammatory cytokines (IL-10, IL-18) and Treg responses [198, 199] These SCFAs also suppress pro-inflammatory histone deacetylase (HDAC), NF-B and nitric oxide production, thus diminishing oxidative stress-induced epithelial cell apoptosis, and exerting a protective effect on colonic and cardiac health [199]

Prime Labs Glutathione (GSH) is a high-purity, lyophilized tripeptide (L-gamma-glutamyl-L-cysteinyl-glycine) synthesized for advanced laboratory research

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Healthspan: The portion of life spent in good health and functional independence in which an individual remains free from significant disease, illnesses or chronic health conditions that substantially impact daily living