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In 2023, the agency reclassified BPC-157 and 18 other manmade peptides as Category 2 Bulk Drug Substances, effectively barring compounding pharmacies from producing them, citing safety concerns and insufficient information on their effects in humans

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Drug Des Dev Ther 9:24852499 Ilic S, Brcic I, Mester M et al (2009) Over-dose insulin and stable gastric pentadecapeptide BPC 157

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis

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