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KEGG enrichment analysis showed that upregulated genes were enriched in oxidative phosphorylation, apoptosis and Reactive oxygen species (ROS), indicating the possible damages in placenta (Fig

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The plasma concentration versus time graph does not produce a straight line on semilogrithmic paper but can be broken into two sections and described by the following biexponential equation: FIGURE 4-3 Graphic representation of a one-compartment open model with IV administration and first order elimination