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Additionally, optimizing dosing schedules and timing in combination regimens can maximize therapeutic efficacy while minimizing toxicity to normal tissues

These findings align with the observed glycogen accumulation in the mutant CMs, suggesting a shift towards enhanced glycogen storage as a result of the PRKAG2 mutation

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Biological function summary Glutathione reductase activity supports cellular defense against oxidative stress by regenerating reduced glutathione

Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial

Yasara, N., Premawardhena, A