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10.1111/1758-2229.12905 27 Gmez-JacintoV.Garca-BarreraT.Garbayo-NoresI.Vilchez-LobatoC.Gmez-ArizaJ.-L

Nelson DB, Godoy M, Shewale J, Correa A, Spicer J, Hofstetter WL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG , Roth JA, Antonoff M

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Tamayo et al., 2025

These findings suggest a dual role for iron in M1 macrophages: while endogenous iron sequestration may facilitate ferroptosis, excess extracellular iron may conversely suppress inflammatory activation