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To have better therapeutic efficacy, the mechanism of RA pathogenesis, however, need to be further elucidated, especially the interaction among genetic background, environmental factors and immune system, so that effective drugs or therapeutic strategies can be developed to restore the tipped immune balance in RA

Understanding mechanism, biomarker evidence, and who benefits requires informed provider guidance and baseline assessment

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It complements topical treatments and enhances their effectiveness by addressing the underlying causes of hyperpigmentation from within

In the Pakistani diet, many local fruits are packed with polyphenols, vitamins, and flavonoids that act as natural shields against oxidative damage