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GAP43 is involved in axonal growth and synaptic plasticity, and its high expression is indicative of active neurodevelopment or repair processes

also the first-line choice per ADA guidelines), gabapentin (3001,200mg three times daily widely used, generally well-tolerated), and pregabalin (75150mg twice daily)

In some embodiments, the otic formulation or composition comprises about 4% by weight of the carbomer

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The humanized murine anti-FAP monoclonal antibody F19 [271], known as Sibrotuzumab, showed a specific FAP targeting effect in cancer patients [272]

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