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Proposed Modification to the Rural Wage Index Calculation Methodology As discussed in section III.G.1 of the preamble of this proposed rule, CMS has taken the opportunity to revisit the case law, prior public comments, and the relevant statutory language with regard to its policies involving the treatment of hospitals that have reclassified as rural under section 1886(d)(8)(E) of the Act, as implemented in the regulations under 42 CFR 412.103

Glutathione S-transferases (GSTs) catalyze the attachment of GSH to antibiotics or their reactive byproducts, often leading to inactivation