14 Growth factors such as RPR (Recombinant Platelet-Derived Growth Factor), BMP-2 (Bone Morphogenetic Protein-2), FGF (Fibroblast Growth Factor), VEGF (Vascular Endothelial Growth Factor), TGF- (Transforming Growth Factor-beta), and BGF (Basic Growth Factor) play crucial roles in driving cellular processes by activating specific receptor-mediated signaling pathways that influence cellular proliferation, migration, differentiation, and survival
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Nutrients, 14 (10), 2050
The different CRP isoforms, nCRP, non-native pentameric CRP (nnCRP) and mCRP (175178, 181184), may explain their protective and destructive effects, with nCRP being primarily antiinflammatory inducing Th2/M2 responses, while mCRP being typically proinflammatory inducing Th1/M1 responses (170, 185189)
