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ITCs are electrophilic compounds that have been shown to activate phase II detoxification enzymes, including glutathione S -transferases (GSTs), in several organisms 24,25,26

[37] [38] Chronic consumption of paracetamol is in many cases not of benefit, [25] and may result in abnormal liver function tests, and higher doses may lead to toxicity, including liver failure

Duration of infusion:30-40 minutes

Some people may notice improvements quickly, while others need multiple sessions for optimal results

Conversely, infusions may suit individuals aiming for long-term wellness and preventive health care

Although there are no case reports or case series suggesting increased risk of paracetamol-related toxicity in people with Gilberts syndrome, a number of controlled studies have investigated the effect of this reduction in UGT activity on paracetamol metabolism