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While these are encouraging reports, two recent large meta-analyses concluded that it still not possible to accurately predict the development of bipolar disorder, based on the early phenomenology (75, 76)

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Nakamura J, Oinuma K, Ohtori S, Watanabe A, Shigemura T, Sasho T, Saito M, Suzuki M, Takahashi K, Kishida S

While this procedure offers a definitive cure, it permanently eliminates fertility, causing significant physical and psychological trauma to the patient [8]

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[7] Side effects [edit] Side effects of alcohol and beta blockers include high blood pressure, dizziness, nausea, diarrhea, constipation, slow heartbeat, liver disease, cancer, dementia, and/or impotence or loss of sexual drive