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Upon ligand binding, this presumably membrane-bound receptor transduces intracellular chemical/redox signals that relay messages for the regulation of gene expression, a phenomenon mainly involving the activation of transcription factors [2, 13, 14, 1618, 26, 34, 51, 70]

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Arora et al

310 The full scope of proteins affected by this pathway, estimated at approximately 300 in the mammalian genome, remains to be explored

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Langmuir 40 (15), 77917811