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Since D2HG and L2HG are indistinguishable in standard LC-MS, to determine which 2HG enantiomer(s) is affected, we adapted a chiral N-(p-toluenesulfonyl)-L-phenylalanyl chloride (TSPC) derivation followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis 24,40

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Research models explore its effects on muscle, tendon, nerve, and gastrointestinal healing and repair

When they are mismatched, the result is more damage on top of a problem that already exists

Levothyroxine should be taken on an empty stomach and separated from iron and calcium supplements by at least four hours to avoid impaired absorption