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With iron-chelating properties and monoamine oxidase inhibitory activity, VK-28 derivatives (including M30, M32, and HLA20) target multiple neurodegenerative pathwaysthey suppress oxidative stress-related pathways (e.g., Keap1-Nrf2), modulate the AKT/mTOR pathway, and alleviate -syn aggregation (230)

Diverse Drug Properties: Hydrophilic, hydrophobic, or combination drugs require different encapsulation strategies to maintain stability and therapeutic potency

mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation

If not treated, they can lead to bigger health problems

Plasma samples are not available from the authors

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