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Supplemental doses of vitamin A greater than 10,000 IU (3,000 mcg retinol activity equivalents [RAE]) have been found to be dangerous during the first trimester of pregnancy

However, if the iris is damaged or missing due to trauma or a genetic condition called aniridia, patients will have vision problems and light sensitivity

Administering higher doses led to a significant decrease in placenta and litter weights

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Is it violent

In another phase I clinical trial using CRS-207 combined with pemetrexed and cisplatin for the treatment of malignant pleural mesothelioma, 31 out of 35 patients showed disease control, with one patient achieving complete remission