About Hospira Bacteriostatic Water Hospira (a Pfizer company) is the most recognised brand for bacteriostatic water injection in research and clinical supply chains
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This product is supplied exclusively for laboratory research purposes
PMCID: PMC9794587
It was identified through a medicinal chemistry programme at the University of Texas Health Science Center as the lead NNMT inhibitor candidate among a series of 1-methylquinolinium analogues bearing primary amine substitutions, selected for its combination of high passive membrane permeability (confirmed in PAMPA assays), high active transport membrane permeability (confirmed in bidirectional Caco-2 cell assays), potent NNMT inhibitory activity, and high selectivity including confirmed absence of inhibitory effects on related SAM-dependent methyltransferases or enzymes in the NAD+ salvage pathway
