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The research project was approved by our institution (Universidad Complutense de Madrid) and by the "Real Federacin Hpica Espaola"

The exclusion criteria were the presence of recognized congenital abnormalities, such as hypothyroidism

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Different from PD in which mitochondrial dysfunction and DA-associated OS lead to dopaminergic neuron loss in substantia nigra as reviewed above, schizophrenia patients show no consistent neuropathology [19]