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Sanjana, N

ROS stimulates the extrinsic apoptotic pathway by promoting the ubiquitin degradation of the cellular FADDlike IL1converting enzymeinhibitory protein (cFLIP), which inhibits the formation of deathinducing signaling complex (DISC) via competitively combining with FADD [150]

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Hydroxocobalamin provides a longer-acting effect compared with oral B12 supplements, which reduces the frequency of dosing

More specific studies addressing end-stage renal failure developed as a complication of DM show that this secondary complication is more common in the Asian population than in the UK population